Wednesday, 13 November 2013

Cannabidiol Inhibits Tumor Cells Without Side Effects, Says New Study


A new study published by the National Institute of Health has found that cannabidiol – a cannabis compound – attacks tumor cells, inhibiting them from further growth, by affecting “multiple tumoral features and molecular pathways”.

“In the present study, we found that CBD inhibited U87-MG and T98G cell proliferation and invasiveness in vitro and caused a decrease in the expression of a set of proteins specifically involved in growth, invasion and angiogenesis”, claims the study’s researchers.

“In addition, CBD treatment caused a dose-related down-regulation of ERK and Akt prosurvival signaling pathways in U87-MG and T98G cells and decreased hypoxia inducible factor HIF-1α expression in U87-MG cells.”

They continue; “Taken together, these results provide new insights into the antitumor action of CBD, showing that this cannabinoid affects multiple tumoral features and molecular pathways.”

The study concludes; “As CBD is a non-psychoactive phytocannabinoid that appears to be devoid of side effects, our results support its exploitation as an effective anti-cancer drug in the management of gliomas.”

The study was conducted at the Centre of Neuroscience at the University of Insubria in Italy 
http://www.ncbi.nlm.nih.gov/pubmed/24204703 




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